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Induction of REDD1 Gene Expression in the Liver in Response to Endoplasmic Reticulum Stress is Mediated through a PERK, eIF2α Phosphorylation, ATF4-dependent Cascade
Since the endoplasmic reticulum (ER) plays a vital role in hepatocyte function, it is not surprising that a variety of liver-related diseases are associated with ER stress. As in other tissues, ER stress in the liver leads to generation of the unfolded-protein response resulting in activation of a t...
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| 主要な著者: | , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2012
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3482272/ https://ncbi.nlm.nih.gov/pubmed/23000413 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2012.09.074 |
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