Limited T Cell Receptor Repertoire Diversity in Tuberculosis Patients Correlates with Clinical Severity

BACKGROUND: The importance of CD4(+) and CD8(+) T cells in protection against tuberculosis (TB) is well known, however, the association between changes to the T cell repertoire and disease presentation has never been analyzed. Characterization of T-cells in TB patients in previous study only analyze...

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Detalhes bibliográficos
Main Authors: Luo, Wei, Su, Jin, Zhang, Xiao-Bing, Yang, Zhi, Zhou, Ming-Qian, Jiang, Zhen-Min, Hao, Pei-Pei, Liu, Su-Dong, Wen, Qian, Jin, Qi, Ma, Li
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3482216/
https://ncbi.nlm.nih.gov/pubmed/23110186
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0048117
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