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Mice Lacking the β4 Subunit of the Nicotinic Acetylcholine Receptor Show Memory Deficits, Altered Anxiety- and Depression-Like Behavior, and Diminished Nicotine-Induced Analgesia
RATIONALE: The role of β4-containing nicotinic acetylcholine receptors (nAChRs) in cognition, anxiety, depression, and analgesia in the absence of nicotine is unclear. METHODS: Wild-type (β4(+/+)) and knockout (β4(−/−)) mice for the nAChR β4 subunit were tested in behavioral tests assessing cognitiv...
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| Autors principals: | , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Oxford University Press
2012
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3482014/ https://ncbi.nlm.nih.gov/pubmed/22573727 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ntr/nts107 |
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