Procholeragenoid: a safe and effective antigen for oral immunization against experimental cholera.

The immunogenicity and safety of procholeragenoid, a minimally toxic, heat-induced aggregate of cholera toxin (CT), were studied in enterically immunized rats and dogs. Although 99% less toxic than CT, procholeragenoid was only slightly less efficient in causing jejunal anti-CT responses in rats; in...

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Publicado en:	Infect Immun
Autores principales:	Pierce, N F, Cray, W C, Sacci, J B, Craig, J P, Germanier, R, Fürer, E
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	American Society for Microbiology (ASM) 1983
Materias:	Research Article
Acceso en línea:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC348165/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6602094/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.40.3.1112-1118.1983
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