Procholeragenoid: a safe and effective antigen for oral immunization against experimental cholera.

The immunogenicity and safety of procholeragenoid, a minimally toxic, heat-induced aggregate of cholera toxin (CT), were studied in enterically immunized rats and dogs. Although 99% less toxic than CT, procholeragenoid was only slightly less efficient in causing jejunal anti-CT responses in rats; in...

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Publié dans:	Infect Immun
Auteurs principaux:	Pierce, N F, Cray, W C, Sacci, J B, Craig, J P, Germanier, R, Fürer, E
Format:	Artigo
Langue:	Inglês
Publié:	American Society for Microbiology (ASM) 1983
Sujets:	Research Article
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC348165/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6602094/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.40.3.1112-1118.1983
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