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Procholeragenoid: a safe and effective antigen for oral immunization against experimental cholera.

The immunogenicity and safety of procholeragenoid, a minimally toxic, heat-induced aggregate of cholera toxin (CT), were studied in enterically immunized rats and dogs. Although 99% less toxic than CT, procholeragenoid was only slightly less efficient in causing jejunal anti-CT responses in rats; in...

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Detalhes bibliográficos
Main Authors: Pierce, N F, Cray, W C, Sacci, J B, Craig, J P, Germanier, R, Fürer, E
Formato: Artigo
Idioma:Inglês
Publicado em: 1983
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC348165/
https://ncbi.nlm.nih.gov/pubmed/6602094
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