Association of postmenopausal endogenous sex hormones with global methylation level of leukocyte DNA among Japanese women

BACKGROUND: Although global hypomethylation of leukocyte DNA has been associated with an increased risk of several sites of cancer, including breast cancer, determinants of global methylation level among healthy individuals remain largely unexplored. Here, we examined whether postmenopausal endogeno...

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Détails bibliographiques
Auteurs principaux: Iwasaki, Motoki, Ono, Hiroe, Kuchiba, Aya, Kasuga, Yoshio, Yokoyama, Shiro, Onuma, Hiroshi, Nishimura, Hideki, Kusama, Ritsu, Yoshida, Teruhiko, Tsugane, Shoichiro
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2012
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3481397/
https://ncbi.nlm.nih.gov/pubmed/22839213
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-12-323
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