Association of postmenopausal endogenous sex hormones with global methylation level of leukocyte DNA among Japanese women

BACKGROUND: Although global hypomethylation of leukocyte DNA has been associated with an increased risk of several sites of cancer, including breast cancer, determinants of global methylation level among healthy individuals remain largely unexplored. Here, we examined whether postmenopausal endogeno...

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Hauptverfasser: Iwasaki, Motoki, Ono, Hiroe, Kuchiba, Aya, Kasuga, Yoshio, Yokoyama, Shiro, Onuma, Hiroshi, Nishimura, Hideki, Kusama, Ritsu, Yoshida, Teruhiko, Tsugane, Shoichiro
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2012
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Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3481397/
https://ncbi.nlm.nih.gov/pubmed/22839213
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-12-323
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