Overexpression of Vesicle-associated Membrane Protein (VAMP) 3, but Not VAMP2, Protects Glucose Transporter (GLUT) 4 Protein Translocation in an in Vitro Model of Cardiac Insulin Resistance

Cardiac glucose utilization is regulated by reversible translocation of the glucose transporter GLUT4 from intracellular stores to the plasma membrane. During the onset of diet-induced insulin resistance, elevated lipid levels in the circulation interfere with insulin-stimulated GLUT4 translocation,...

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Hlavní autoři: Schwenk, Robert W., Angin, Yeliz, Steinbusch, Laura K. M., Dirkx, Ellen, Hoebers, Nicole, Coumans, Will A., Bonen, Arend, Broers, Jos L. V., van Eys, Guillaume J. J. M., Glatz, Jan F. C., Luiken, Joost J. F. P.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2012
Témata:
Metabolism
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3481347/
https://ncbi.nlm.nih.gov/pubmed/22936810
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.363630
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