Overexpression of Vesicle-associated Membrane Protein (VAMP) 3, but Not VAMP2, Protects Glucose Transporter (GLUT) 4 Protein Translocation in an in Vitro Model of Cardiac Insulin Resistance

Cardiac glucose utilization is regulated by reversible translocation of the glucose transporter GLUT4 from intracellular stores to the plasma membrane. During the onset of diet-induced insulin resistance, elevated lipid levels in the circulation interfere with insulin-stimulated GLUT4 translocation,...

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Autori principali: Schwenk, Robert W., Angin, Yeliz, Steinbusch, Laura K. M., Dirkx, Ellen, Hoebers, Nicole, Coumans, Will A., Bonen, Arend, Broers, Jos L. V., van Eys, Guillaume J. J. M., Glatz, Jan F. C., Luiken, Joost J. F. P.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2012
Soggetti:
Metabolism
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3481347/
https://ncbi.nlm.nih.gov/pubmed/22936810
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.363630
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