Protein Kinase D1 Is Essential for Contraction-induced Glucose Uptake but Is Not Involved in Fatty Acid Uptake into Cardiomyocytes

Increased contraction enhances substrate uptake into cardiomyocytes via translocation of the glucose transporter GLUT4 and the long chain fatty acid (LCFA) transporter CD36 from intracellular stores to the sarcolemma. Additionally, contraction activates the signaling enzymes AMP-activated protein ki...

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Bibliographic Details
Main Authors: Dirkx, Ellen, Schwenk, Robert W., Coumans, Will A., Hoebers, Nicole, Angin, Yeliz, Viollet, Benoit, Bonen, Arend, van Eys, Guillaume J. J. M., Glatz, Jan F. C., Luiken, Joost J. F. P.
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2012
Subjects:
Metabolism
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3285356/
https://ncbi.nlm.nih.gov/pubmed/22158620
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.281881
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