Protein Kinase D1 Is Essential for Contraction-induced Glucose Uptake but Is Not Involved in Fatty Acid Uptake into Cardiomyocytes

Increased contraction enhances substrate uptake into cardiomyocytes via translocation of the glucose transporter GLUT4 and the long chain fatty acid (LCFA) transporter CD36 from intracellular stores to the sarcolemma. Additionally, contraction activates the signaling enzymes AMP-activated protein ki...

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Bibliografiska uppgifter
Huvudupphovsmän: Dirkx, Ellen, Schwenk, Robert W., Coumans, Will A., Hoebers, Nicole, Angin, Yeliz, Viollet, Benoit, Bonen, Arend, van Eys, Guillaume J. J. M., Glatz, Jan F. C., Luiken, Joost J. F. P.
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Biochemistry and Molecular Biology 2012
Ämnen:
Metabolism
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3285356/
https://ncbi.nlm.nih.gov/pubmed/22158620
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.281881
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