Orphan Nuclear Receptor Small Heterodimer Partner Negatively Regulates Growth Hormone-mediated Induction of Hepatic Gluconeogenesis through Inhibition of Signal Transducer and Activator of Transcription 5 (STAT5) Transactivation

Growth hormone (GH) is a key metabolic regulator mediating glucose and lipid metabolism. Ataxia telangiectasia mutated (ATM) is a member of the phosphatidylinositol 3-kinase superfamily and regulates cell cycle progression. The orphan nuclear receptor small heterodimer partner (SHP: NR0B2) plays a p...

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Autori principali: Kim, Yong Deuk, Li, Tiangang, Ahn, Seung-Won, Kim, Don-Kyu, Lee, Ji-Min, Hwang, Seung-Lark, Kim, Yong-Hoon, Lee, Chul-Ho, Lee, In-Kyu, Chiang, John Y. L., Choi, Hueng-Sik
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2012
Soggetti:
Gene Regulation
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3481310/
https://ncbi.nlm.nih.gov/pubmed/22977252
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.339887
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