Specific Function of the Met-Tyr-Trp Adduct Radical and Residues Arg-418 and Asp-137 in the Atypical Catalase Reaction of Catalase-Peroxidase KatG

Míreanna Comhchosúla

• A radical on the Met-Tyr-Trp modification required for catalase activity in catalase-peroxidase is established by isotopic labeling and site-directed mutagenesis
  le: Zhao, Xiangbo, et al.
  Foilsithe: (2010)
• Access channel residues Ser315 and Asp137 in Mycobacterium tuberculosis catalase-peroxidase (KatG) control peroxidatic activation of the pro-drug isoniazid
  le: Zhao, Xiangbo, et al.
  Foilsithe: (2013)
• Modification of the active site of Mycobacterium tuberculosis KatG after disruption of the Met-Tyr-Trp cross-linked adduct
  le: Kapetanaki, Sofia M., et al.
  Foilsithe: (2006)
• An Oxyferrous Heme/Protein-based Radical Intermediate Is Catalytically Competent in the Catalase Reaction of Mycobacterium tuberculosis Catalase-Peroxidase (KatG)
  le: Suarez, Javier, et al.
  Foilsithe: (2009)
• Characterization of the W321F mutant of Mycobacterium tuberculosis catalase–peroxidase KatG
  le: Yu, Shengwei, et al.
  Foilsithe: (2002)