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N-Myristoylation and Ca(2+) Binding of Calcineurin B Homologous Protein CHP3 Are Required to Enhance Na(+)/H(+) Exchanger NHE1 Half-life and Activity at the Plasma Membrane
Calcineurin B homologous proteins (CHP) are N-myristoylated, EF-hand Ca(2+)-binding proteins that regulate multiple cellular processes, including intracellular pH homeostasis. Previous work has shown that the heart-enriched isoform, CHP3, regulates the plasmalemmal Na(+)/H(+) exchanger NHE1 isoform...
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| Autori principali: | , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Society for Biochemistry and Molecular Biology
2012
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3481291/ https://ncbi.nlm.nih.gov/pubmed/22984264 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.394700 |
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