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Crystallization and preliminary crystallographic analysis of the human calcineurin homologous protein CHP2 bound to the cytoplasmic region of the Na(+)/H(+) exchanger NHE1

Calcineurin homologous protein (CHP) is a Ca(2+)-binding protein that directly interacts with and regulates the activity of all plasma-membrane Na(+)/H(+)-exchanger (NHE) family members. In contrast to the ubiquitous isoform CHP1, CHP2 is highly expressed in cancer cells. To understand the regulator...

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Autors principals: Ben Ammar, Youssef, Takeda, Soichi, Sugawara, Mitsuaki, Miyano, Masashi, Mori, Hidezo, Wakabayashi, Shigeo
Format: Artigo
Idioma:Inglês
Publicat: International Union of Crystallography 2005
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1991313/
https://ncbi.nlm.nih.gov/pubmed/16511206
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S1744309105030836
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