Llwytho...

Crystal structure of CHP2 complexed with NHE1-cytosolic region and an implication for pH regulation

The plasma membrane Na(+)/H(+) exchangers (NHE) require calcineurin B homologous protein (CHP) as an obligatory binding partner for ion transport. Here, we report the first crystal structure of CHP (CHP2 isoform) in complex with its binding domain in NHE1. We show that the cytoplasmic α-helix of NHE...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Ammar, Youssef Ben, Takeda, Soichi, Hisamitsu, Takashi, Mori, Hidezo, Wakabayashi, Shigeo
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2006
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC1478177/
https://ncbi.nlm.nih.gov/pubmed/16710297
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601145
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