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Neurologic and motor dysfunctions in APP transgenic mice

The discovery of gene mutations underlying autosomal dominant Alzheimer’s disease has enabled researchers to reproduce several hallmarks of this disorder in transgenic mice, notably the formation of Aβ plaques in brain and cognitive deficits. APP transgenic mutants have also been investigated with r...

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Detalhes bibliográficos
Main Authors: Lalonde, Robert, Fukuchi, Ken-ichiro, Strazielle, Catherine
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3481185/
https://ncbi.nlm.nih.gov/pubmed/23089603
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1515/revneuro-2012-0041
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