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APP transgenic mice for modelling behavioral and psychological symptoms of dementia (BPSD)
The discovery of gene mutations responsible for autosomal dominant Alzheimer's disease has enabled researchers to reproduce in transgenic mice several hallmarks of this disorder, notably Aβ accumulation, though in most cases without neurofibrillary tangles. Mice expressing mutated and wild-type...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3340431/ https://ncbi.nlm.nih.gov/pubmed/22373961 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neubiorev.2012.02.011 |
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