The microRNA-26a target E2F7 sustains cell proliferation and inhibits monocytic differentiation of acute myeloid leukemia cells

Blocks in genetic programs required for terminal myeloid differentiation and aberrant proliferation characterize acute myeloid leukemia (AML) cells. 1,25-Dihydroxy-vitamin D3 (VitD3) arrests proliferation of AML cells and induces their differentiation into mature monocytes. In a previous study, we s...

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Bibliographic Details
Main Authors: Salvatori, B, Iosue, I, Mangiavacchi, A, Loddo, G, Padula, F, Chiaretti, S, Peragine, N, Bozzoni, I, Fazi, F, Fatica, A
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2012
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Original Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3481138/
https://ncbi.nlm.nih.gov/pubmed/23096114
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2012.151
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