The microRNA-26a target E2F7 sustains cell proliferation and inhibits monocytic differentiation of acute myeloid leukemia cells

Blocks in genetic programs required for terminal myeloid differentiation and aberrant proliferation characterize acute myeloid leukemia (AML) cells. 1,25-Dihydroxy-vitamin D3 (VitD3) arrests proliferation of AML cells and induces their differentiation into mature monocytes. In a previous study, we s...

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Detalhes bibliográficos
Main Authors: Salvatori, B, Iosue, I, Mangiavacchi, A, Loddo, G, Padula, F, Chiaretti, S, Peragine, N, Bozzoni, I, Fazi, F, Fatica, A
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2012
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3481138/
https://ncbi.nlm.nih.gov/pubmed/23096114
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2012.151
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