Regulatory B Cells from Hilar Lymph Nodes of Tolerant Mice in a Murine Model of Allergic Airway Disease are CD5(+), Express TGF-β and Co-localize with CD4(+)Foxp3(+) T Cells

In a biphasic, ovalbumin (OVA)-induced murine asthma model where allergic airway disease is followed by resolution and the development of local inhalational tolerance (LIT), TGFβ-expressing CD5(+) B cells were selectively expanded locally in hilar lymph nodes (HLN) of LIT mice. LIT HLN CD5(+) B cell...

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Bibliographic Details
Main Authors: Natarajan, Prabitha, Singh, Anurag, McNamara, Jeffrey T., Secor, Eric R., Guernsey, Linda A., Thrall, Roger S., Schramm, Craig M.
Format: Artigo
Language:Inglês
Published: 2012
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3480990/
https://ncbi.nlm.nih.gov/pubmed/22718263
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mi.2012.42
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