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Accumulation of Regulatory T Cells in Local Draining Lymph Nodes of the Lung Correlates with Spontaneous Resolution of Chronic Asthma in a Murine Model

BACKGROUND: Mice sensitized to ovalbumin develop allergic airway disease (AAD) with short-term aerosol challenge; however, airway inflammation resolves with long-term aerosol challenge, referred to as local inhalational tolerance (LIT). METHODS: We sought to determine if resolution of airway inflamm...

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Main Authors: Carson, William F., Guernsey, Linda A., Singh, Anurag, Vella, Anthony T., Schramm, Craig M., Thrall, Roger S.
格式: Artigo
語言:Inglês
出版: 2007
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2576511/
https://ncbi.nlm.nih.gov/pubmed/17914275
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000109292
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