Phenotypic Changes to the Endogenous Antigen-Specific CD8(+) T Cell Response Correlates with the Development and Resolution of Allergic Airway Disease

The role of CD8(+) T cells in the pathogenesis of asthma remains controversial, as both pro- and anti-inflammatory functions have been suggested. This study was designed to examine the endogenous CD8(+) T cell response in a biphasic ovalbumin (OVA)–induced model of allergic airway disease (AAD) and...

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Hlavní autoři: McNamara, Jeffrey T., Schramm, Craig M., Singh, Anurag, Secor, Eric R., Guernsey, Linda A., Lefrançois, Leo, Thrall, Roger S.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Investigative Pathology 2012
Témata:
Regular Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3349839/
https://ncbi.nlm.nih.gov/pubmed/22452921
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2012.01.043
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