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Targeted Gene Correction of Laminopathy-Associated LMNA Mutations in Patient-Specific iPSCs
Combination of stem cell-based approaches with gene-editing technologies represents an attractive strategy for studying human disease and developing therapies. However, gene-editing methodologies described to date for human cells suffer from technical limitations including limited target gene size,...
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Asıl Yazarlar: | , , , , , , , , , , , , , , , , , |
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Materyal Türü: | Artigo |
Dil: | Inglês |
Baskı/Yayın Bilgisi: |
2011
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Konular: | |
Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3480729/ https://ncbi.nlm.nih.gov/pubmed/21596650 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stem.2011.04.019 |
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