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Sigma-1R Agonist Improves Motor Function and Motoneuron Survival in ALS Mice
Amyotrophic lateral sclerosis is a neurodegenerative disorder characterized by progressive weakness, muscle atrophy, and paralysis due to the loss of upper and lower motoneurons (MNs). Sigma-1 receptor (sigma-1R) activation promotes neuroprotection after ischemic and traumatic injuries to the centra...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Springer-Verlag
2012
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3480575/ https://ncbi.nlm.nih.gov/pubmed/22935988 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13311-012-0140-y |
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