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Phosphorylation of MeCP2 at Ser421 Contributes to Chronic Antidepressant Action

Although tricyclic antidepressants rapidly activate monoaminergic neurotransmission, these drugs must be administered chronically to alleviate symptoms of depression. This observation suggests that molecular mechanisms downstream of monoamine receptor activation, which include the induction of gene...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Hutchinson, Ashley N., Deng, Jay V., Cohen, Sonia, West, Anne E.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Society for Neuroscience 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3480513/
https://ncbi.nlm.nih.gov/pubmed/23055506
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2156-12.2012
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