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Phosphorylation of MeCP2 at Ser421 Contributes to Chronic Antidepressant Action

Although tricyclic antidepressants rapidly activate monoaminergic neurotransmission, these drugs must be administered chronically to alleviate symptoms of depression. This observation suggests that molecular mechanisms downstream of monoamine receptor activation, which include the induction of gene...

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Detalhes bibliográficos
Main Authors: Hutchinson, Ashley N., Deng, Jay V., Cohen, Sonia, West, Anne E.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3480513/
https://ncbi.nlm.nih.gov/pubmed/23055506
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2156-12.2012
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