An Essential Role for Histone Deacetylase 4 in Synaptic Plasticity and Memory Formation

Histone deacetylases (HDACs), a family of enzymes involved in epigenetic regulation, have been implicated in the control of synaptic plasticity, as well as learning and memory. Previous work has demonstrated administration of pharmacological HDAC inhibitors, primarily those targeted to class I HDACs...

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Autors principals: Kim, Mi-Sung, Akhtar, M. Waseem, Adachi, Megumi, Mahgoub, Melissa, Bassel-Duby, Rhonda, Kavalali, Ege T., Olson, Eric N., Monteggia, Lisa M.
Format: Artigo
Idioma:Inglês
Publicat: Society for Neuroscience 2012
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Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3480333/
https://ncbi.nlm.nih.gov/pubmed/22875922
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2089-12.2012
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