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Partial Reduction of Human FOXP3+ CD4 T Cells In Vivo After CD25-directed Recombinant Immunotoxin Administration
The regulation of tolerance to self-proteins and the suppression of T-cell responses have in part been attributed to the activity of CD25(+)CD4(+) T regulatory (T(reg)) cells. Further, T(reg) cells can inhibit the antitumor effectiveness of adoptive immunotherapy and active immunization approaches i...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3480218/ https://ncbi.nlm.nih.gov/pubmed/18481388 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/CJI.0b013e31815dc0e8 |
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