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Extended model-based designs for more complex dose-finding studies
We discuss extensions of model-based designs, such as the continual reassessment method, for use in dose-finding studies. Rather than work with a single model to carry out the design and analysis of a dose-finding study we indicate how the use of several models can greatly increase flexibility. We c...
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| 主要な著者: | , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2011
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3480175/ https://ncbi.nlm.nih.gov/pubmed/21351287 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/sim.4024 |
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