Comparison of the D2 Receptor Regulation and Neurotoxicant Susceptibility of Nigrostriatal Dopamine Neurons in Wild-Type and CB1/CB2 Receptor Knockout Mice

Motor dysfunctions of Parkinson Disease (PD) are due to the progressive loss of midbrain nigrostriatal dopamine (NSDA) neurons. Evidence suggests a role for cannabinoid receptors in the neurodegeneration of these neurons following neurotoxicant-induced injury. This work evaluates NSDA neurons in CB1...

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Detalhes bibliográficos
Main Authors: Simkins, Tyrell J., Janis, Kelly L., McClure, Alison K., Behrouz, Bahareh, Pappas, Samuel S., Lehner, Andreas, Kaminski, Norbert E., Goudreau, John L., Lookingland, Keith J., Kaplan, Barbara L. F.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3479639/
https://ncbi.nlm.nih.gov/pubmed/22639229
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11481-012-9375-y
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