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Top-down approach for the direct characterization of low molecular weight heparins using LC-FT-MS

Low molecular heparins (LMWHs) are structurally complex, heterogeneous, polydisperse, and highly negatively charged mixtures of polysaccharides. The direct characterization of LMWH is a major challenge for currently available analytical technologies. Electrospray ionization (ESI) liquid chromatograp...

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Hlavní autoři: Li, Lingyun, Zhang, Fuming, Zaia, Joseph, Linhardt, Robert J.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3479637/
https://ncbi.nlm.nih.gov/pubmed/22985071
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ac302232c
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