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Top-down approach for the direct characterization of low molecular weight heparins using LC-FT-MS
Low molecular heparins (LMWHs) are structurally complex, heterogeneous, polydisperse, and highly negatively charged mixtures of polysaccharides. The direct characterization of LMWH is a major challenge for currently available analytical technologies. Electrospray ionization (ESI) liquid chromatograp...
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| Autors principals: | , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2012
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3479637/ https://ncbi.nlm.nih.gov/pubmed/22985071 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ac302232c |
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