Calcium-activated chloride channel TMEM16A modulates mucin secretion and airway smooth muscle contraction

Mucous cell hyperplasia and airway smooth muscle (ASM) hyperresponsiveness are hallmark features of inflammatory airway diseases, including asthma. Here, we show that the recently identified calcium-activated chloride channel (CaCC) TMEM16A is expressed in the adult airway surface epithelium and ASM...

Description complète

Enregistré dans:
Détails bibliographiques
Auteurs principaux: Huang, Fen, Zhang, Hongkang, Wu, Meng, Yang, Huanghe, Kudo, Makoto, Peters, Christian J., Woodruff, Prescott G., Solberg, Owen D., Donne, Matthew L., Huang, Xiaozhu, Sheppard, Dean, Fahy, John V., Wolters, Paul J., Hogan, Brigid L. M., Finkbeiner, Walter E., Li, Min, Jan, Yuh-Nung, Jan, Lily Yeh, Rock, Jason R.
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 2012
Sujets:
Biological Sciences
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3479591/
https://ncbi.nlm.nih.gov/pubmed/22988107
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1214596109
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!

Documents similaires