Calcium-activated chloride channel TMEM16A modulates mucin secretion and airway smooth muscle contraction

Mucous cell hyperplasia and airway smooth muscle (ASM) hyperresponsiveness are hallmark features of inflammatory airway diseases, including asthma. Here, we show that the recently identified calcium-activated chloride channel (CaCC) TMEM16A is expressed in the adult airway surface epithelium and ASM...

詳細記述

保存先:
書誌詳細
主要な著者: Huang, Fen, Zhang, Hongkang, Wu, Meng, Yang, Huanghe, Kudo, Makoto, Peters, Christian J., Woodruff, Prescott G., Solberg, Owen D., Donne, Matthew L., Huang, Xiaozhu, Sheppard, Dean, Fahy, John V., Wolters, Paul J., Hogan, Brigid L. M., Finkbeiner, Walter E., Li, Min, Jan, Yuh-Nung, Jan, Lily Yeh, Rock, Jason R.
フォーマット: Artigo
言語:Inglês
出版事項: National Academy of Sciences 2012
主題:
Biological Sciences
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3479591/
https://ncbi.nlm.nih.gov/pubmed/22988107
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1214596109
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