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Dependence on nuclear factor of activated T-cells (NFAT) levels discriminates conventional T cells from Foxp3(+) regulatory T cells

Several lines of evidence suggest nuclear factor of activated T-cells (NFAT) to control regulatory T cells: thymus-derived naturally occurring regulatory T cells (nTreg) depend on calcium signals, the Foxp3 gene harbors several NFAT binding sites, and the Foxp3 (Fork head box P3) protein interacts w...

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Detalhes bibliográficos
Main Authors: Vaeth, Martin, Schliesser, Ulrike, Müller, Gerd, Reissig, Sonja, Satoh, Kazuki, Tuettenberg, Andrea, Jonuleit, Helmut, Waisman, Ari, Müller, Martin R., Serfling, Edgar, Sawitzki, Birgit S., Berberich-Siebelt, Friederike
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3479579/
https://ncbi.nlm.nih.gov/pubmed/22991461
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1203870109
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