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NFATc1 affects mouse splenic B cell function by controlling the calcineurin–NFAT signaling network
By studying mice in which the Nfatc1 gene was inactivated in bone marrow, spleen, or germinal center B cells, we show that NFATc1 supports the proliferation and suppresses the activation-induced cell death of splenic B cells upon B cell receptor (BCR) stimulation. BCR triggering leads to expression...
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| 主要な著者: | , , , , , , , , , , , , , , , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
The Rockefeller University Press
2011
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3135343/ https://ncbi.nlm.nih.gov/pubmed/21464221 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20100945 |
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