NFATc1 affects mouse splenic B cell function by controlling the calcineurin–NFAT signaling network

By studying mice in which the Nfatc1 gene was inactivated in bone marrow, spleen, or germinal center B cells, we show that NFATc1 supports the proliferation and suppresses the activation-induced cell death of splenic B cells upon B cell receptor (BCR) stimulation. BCR triggering leads to expression...

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Main Authors: Bhattacharyya, Sankar, Deb, Jolly, Patra, Amiya K., Thuy Pham, Duong Anh, Chen, Wen, Vaeth, Martin, Berberich-Siebelt, Friederike, Klein-Hessling, Stefan, Lamperti, Edward D., Reifenberg, Kurt, Jellusova, Julia, Schweizer, Astrid, Nitschke, Lars, Leich, Ellen, Rosenwald, Andreas, Brunner, Cornelia, Engelmann, Swen, Bommhardt, Ursula, Avots, Andris, Müller, Martin R., Kondo, Eisaku, Serfling, Edgar
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3135343/
https://ncbi.nlm.nih.gov/pubmed/21464221
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20100945
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