Intracellular Calcium Dynamics, Shortened Action Potential Duration and Late-phase 3 Early Afterdepolarization in Langendorff-Perfused Rabbit Ventricles

INTRODUCTION: To elucidate the mechanism of late-phase 3 early after depolarization (EAD) in ventricular arrhythmogenesis, we hypothesized that intracellular calcium (Ca(i)) overloading and action potential duration (APD) shortening may promote late phase 3 EAD and triggered activity, leading to dev...

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Hauptverfasser: Tang, Liang, Joung, Boyoung, Ogawa, Masahiro, Chen, Peng-Sheng, Lin, Shien-Fong
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2012
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3479328/
https://ncbi.nlm.nih.gov/pubmed/22809087
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1540-8167.2012.02400.x
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