Hypokalemia Promotes Late Phase 3 Early Afterdepolarization and Recurrent Ventricular Fibrillation During Isoproterenol Infusion in Langendorff Perfused Rabbit Ventricles

BACKGROUND: Hypokalemia and sympathetic activation are commonly associated with electrical storm (ES) in normal and diseased hearts. The mechanisms remain unclear. OBJECTIVE: To test the hypothesis that late phase 3 early afterdepolarization (EAD) induced by I(KATP) activation underlies the mechanis...

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Détails bibliographiques
Auteurs principaux: Maruyama, Mitsunori, Ai, Tomohiko, Chua, Su-Kiat, Park, Hyung-Wook, Lee, Young-Soo, Shen, Mark J., Chang, Po-Cheng, Lin, Shien-Fong, Chen, Peng-Sheng
Format: Artigo
Langue:Inglês
Publié: 2013
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3996562/
https://ncbi.nlm.nih.gov/pubmed/24378768
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.hrthm.2013.12.032
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