Variants in the LEPR gene are nominally associated with higher BMI and lower 24 hour energy expenditure in Pima Indians

Genome-wide association studies (GWASs) have been used to search for susceptibility genes for type 2 diabetes and obesity in the Pima Indians, a population with high a prevalence of both diseases. In these studies, a variant (rs2025804) in the LEPR gene was nominally associated with BMI in 1082 subj...

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Bibliographic Details
Main Authors: Traurig, Michael, Perez, Jessica, Ma, Lijun, Bian, Li, Kobes, Sayuko, Hanson, Robert L., Knowler, William C., Krakoff, Jonathan, Bogardus, Clifton, Baier, Leslie J.
Format: Artigo
Language:Inglês
Published: 2012
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3479320/
https://ncbi.nlm.nih.gov/pubmed/22810975
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/oby.2012.159
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