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Apigenin Inhibits NNK-induced Focal Adhesion Kinase Activation in Pancreatic Cancer Cells
OBJECTIVES: Tobacco-derived carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone, NNK, activates β-adrenergic receptor (β-AR) signaling through Src/focal adhesion kinases (FAK)/MAPK to modulate proliferation, migration and survival. Apigenin (4′, 5, 7-trihydroxyflavone) is reported to attenuate...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3479318/ https://ncbi.nlm.nih.gov/pubmed/22889981 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/MPA.0b013e31824d64d9 |
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