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Loss of 15-Hydroxyprostaglandin Dehydrogenase Increases Prostaglandin E(2) in Pancreatic Tumors
OBJECTIVES: Prostaglandin E(2) (PGE(2)) is a product of cyclooxygenase (COX) and prostaglandin E synthase (PGES) and deactivated by 15-hydroxyprostaglandin dehydrogenase (PGDH). Down-regulation of PGDH contributes to PGE(2) accumulation in lung and colon cancers but has not been identified in pancre...
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| Main Authors: | , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2859226/ https://ncbi.nlm.nih.gov/pubmed/19820419 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/MPA.0b013e3181baecbe |
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