Loss of 15-Hydroxyprostaglandin Dehydrogenase Increases Prostaglandin E(2) in Pancreatic Tumors

OBJECTIVES: Prostaglandin E(2) (PGE(2)) is a product of cyclooxygenase (COX) and prostaglandin E synthase (PGES) and deactivated by 15-hydroxyprostaglandin dehydrogenase (PGDH). Down-regulation of PGDH contributes to PGE(2) accumulation in lung and colon cancers but has not been identified in pancre...

Full description

Saved in:

Bibliographic Details
Main Authors:	Pham, Hung, Chen, Monica, Li, Aihua, King, Jonathan, Angst, Eliane, Dawson, David W., Park, Jenny, Reber, Howard A., O. Joe, Hines, Eibl, Guido
Format:	Artigo
Language:	Inglês
Published:	2010
Subjects:	Article
Online Access:	https://ncbi.nlm.nih.gov/pmc/articles/PMC2859226/ https://ncbi.nlm.nih.gov/pubmed/19820419 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/MPA.0b013e3181baecbe
Tags:	Add Tag No Tags, Be the first to tag this record!

Loss of 15-Hydroxyprostaglandin Dehydrogenase Increases Prostaglandin E(2) in Pancreatic Tumors

Similar Items