Epigenetic regulation affects N-myc downstream regulated gene-1 expression indirectly in pancreatic cancer cells

OBJECTIVES: N-myc downstream regulated gene-1 (NDRG1), important in tumor growth and metastasis, has recently gained interest as a potential therapeutic target. Loss of NDRG1 expression is generally associated with poor clinical outcome in pancreatic cancer (PaCa) patients. As the NDRG1 gene possess...

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Bibliographic Details
Main Authors: Angst, Eliane, Dawson, David W., Nguyen, Anne, Park, Jenny, Go, Vay L.W., Reber, Howard A., Hines, O. Joe, Eibl, Guido
Format: Artigo
Language:Inglês
Published: 2010
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2895953/
https://ncbi.nlm.nih.gov/pubmed/20173668
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/MPA.0b013e3181c8b476
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