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4-Isoxazolyl-1,4-dihydropyridines exhibit binding at the multidrug resistance transporter
[Image: see text] The 4-Isoxazolyl-dihydropyridines (IDHPs) exhibit inhibition of the multidrug-resistance transporter (MDR-1), and exhibit an SAR distinct from their activity at voltage gated calcium channels (VGCC). Among the four most active IDHPs, three were branched at C-5 of the isoxazole, inc...
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| Главные авторы: | , , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2012
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3479305/ https://ncbi.nlm.nih.gov/pubmed/23063517 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2012.09.022 |
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