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The role of Ca(2+) in the activity of Mycobacterium tuberculosis DNA gyrase

DNA gyrase is the only type II topoisomerase in Mycobacterium tuberculosis and needs to catalyse DNA supercoiling, relaxation and decatenation reactions in order to fulfil the functions normally carried out by gyrase and DNA topoisomerase IV in other bacteria. We have obtained evidence for the exist...

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Autori principali: Karkare, Shantanu, Yousafzai, Faridoon, Mitchenall, Lesley A., Maxwell, Anthony
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3479174/
https://ncbi.nlm.nih.gov/pubmed/22844097
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gks704
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