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Glutamate racemase from Mycobacterium tuberculosis inhibits DNA gyrase by affecting its DNA-binding

Glutamate racemase (MurI) catalyses the conversion of l-glutamate to d-glutamate, an important component of the bacterial cell wall. MurI from Escherichia coli inhibits DNA gyrase in presence of the peptidoglycan precursor. Amongst the two-glutamate racemases found in Bacillus subtilis, only one inh...

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Bibliografiske detaljer
Main Authors: Sengupta, Sugopa, Shah, Meera, Nagaraja, Valakunja
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2006
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1635304/
https://ncbi.nlm.nih.gov/pubmed/17020913
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkl704
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