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Induction of tumoricidal function in CD4(+) T cells is associated with concomitant memory and terminally differentiated phenotype
Harnessing the adaptive immune response to treat malignancy is now a clinical reality. Several strategies are used to treat melanoma; however, very few result in a complete response. CD4(+) T cells are important and potent mediators of anti-tumor immunity and adoptive transfer of specific CD4(+) T c...
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| Main Authors: | , , , , , , , , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
The Rockefeller University Press
2012
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3478933/ https://ncbi.nlm.nih.gov/pubmed/23008334 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20120532 |
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