Human lymphoma mutations reveal CARD11 as the switch between self-antigen–induced B cell death or proliferation and autoantibody production

Self-tolerance and immunity are actively acquired in parallel through a poorly understood ability of antigen receptors to switch between signaling death or proliferation of antigen-binding lymphocytes in different contexts. It is not known whether this tolerance-immunity switch requires global rewir...

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Hlavní autoři: Jeelall, Yogesh S., Wang, James Q., Law, Hsei-Di, Domaschenz, Heather, Fung, Herman K.H., Kallies, Axel, Nutt, Stephen L., Goodnow, Christopher C., Horikawa, Keisuke
Médium: Artigo
Jazyk:Inglês
Vydáno: The Rockefeller University Press 2012
Témata:
Brief Definitive Report
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3478930/
https://ncbi.nlm.nih.gov/pubmed/23027925
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20112744
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