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Comparison of DNA-Reactive Metabolites from Nitrosamine and Styrene Using Voltammetric DNA/Microsomes Sensors

Voltammetric sensors made with films of polyions, double-stranded DNA and liver microsomes adsorbed layer-by-layer onto pyrolytic graphite electrodes were evaluated for reactive metabolite screening. This approach features simple, inexpensive screening without enzyme purification for applications in...

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Detalhes bibliográficos
Main Authors: Krishnan, Sadagopan, Bajrami, Besnik, Mani, Vigneshwaran, Pan, Shenmin, Rusling, James F.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3478694/
https://ncbi.nlm.nih.gov/pubmed/23100998
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/elan.200804521
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